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Serious side effects requiring immediate medical attention: pancreatitis (severe, persistent abdominal pain), kidney complications from dehydration caused by nausea, vomiting, or diarrhea, acute gallbladder disease, diabetic retinopathy changes in patients with type 2 diabetes, severe gastrointestinal disease, hypoglycemia when combined with insulin or sulfonylureas, increasing heart rate, and worsening depression or suicidal ideation

Repeatedly using the same spot can cause hardening of the tissue (lipodystrophy), which can affect absorption

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